Comparison of performance characteristics between high‐performance liquid chromatography and latex agglutination turbidimetric immunoassay for therapeutic drug monitoring of zonisamide

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DOI:  https://doi.org/10.1002/jcla.22940
Fecha: 20 junio 2019
Revista: Journal
Autores: Daiki Eto, Ryota Tanaka, Yosuke Suzuki, Yuhki Sato, Hiroki Itoh

Background: Recently, the Nanopia® TDM Zonisamide reagent using the latex particle‐enhanced turbidimetric immunoassay (LTIA) method was developed. The aim of this study was to compare the differences in serum zonisamide (ZNS) concentrations quantified by the high‐performance liquid chromatography (HPLC) method and the LTIA method using a TBA‐25FR analyzer.